In India, it's quite a curiosity whether a plane would take off with just one passenger on board. In theory, it's possible, as there are no regulations preventing it. However, it's unlikely due to economic reasons - airlines often need to ensure a minimum number of passengers to cover costs. Yet, in extreme situations, such as emergencies or when a passenger is of high importance, it might happen. So, while it's not a common occurrence, it's not entirely out of the question.